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Responding to the call for action during the COVID-19 pandemic
Quickly after the COVID-19 pandemic began to grip the world, Lawson Health Research Institute responded with action. Lawson is the research arm of London Health Sciences Centre (LHSC) and St. Joseph’s Health Care London. With hospitals focused on providing excellent patient care in the face of an unknown virus, hospital researchers in London, Ontario began critical COVID-19 studies.
“A lot was unknown during the first wave of the pandemic. Any research that wasn’t essential was put on hold. At the same time, we had people with different expertise coming together with different perspectives to see how we could better understand the SARS-CoV-2 virus and the COVID-19 infection,” explains Dr. David Hill, Lawson Scientific Director and VP, Research at LHSC and. St. Joseph's. “Our hospital researchers formulated ideas and very quickly came up with research proposals. These were fast tracked through our processes and within two months we approved over 50 new studies surrounding COVID-19.”
Dr. David Hill, Lawson Scientific Director and VP, Research at LHSC and. St. Joseph's
Some of these studies were clinical trials, which are research studies performed with people. Many patients from London hospitals get involved as patient participants and when COVID-19 hit, many agreed to be a part of this important research.
“We saw the pandemic happening across the world, and suddenly it was happening here in London. This has probably been the biggest challenge of my career,” says Carol Young-Ritchie, Executive Vice President at LHSC. “We had to look at many of our processes and how we were doing things, and adjust appropriately and nimbly.”
Young-Ritchie adds that as the hospital continued to admit a growing number of COVID-19 patients, a strong focus on research was needed. “It was absolutely critical and important for LHSC as a leader and academic centre to contribute to our collective knowledge. We needed to keep that research going and although it has been challenging, it has also taught us to be innovative.”
Carol Young-Ritchie, Executive Vice President at LHSC
The same focus was happening at St. Joseph’s Health Care London, with health care providers and researchers finding ways to improve care and outcomes for patients who had contracted the virus. “COVID-19 research through the hospital has been incredibly important,” says Karen Perkin, Vice President of Patient Care at St. Joseph’s. “We had researchers busy looking at the impacts of COVID-19. We had patients on ventilators and we were trying to understand that more. We also had research looking at the impacts for staff members looking after patients. All important, helpful knowledge as we move forward.”
Karen Perkin, Vice President of Patient Care at St. Joseph’s
Hospital research in London through Lawson is proudly affiliated with Western University. At Western’s Schulich School of Medicine & Dentistry, the new state-of-the-art Imaging Pathogens for Knowledge Translation (ImPaKT) Facility was the perfect environment to conduct COVID-19 research.
“ImPaKT is a special containment facility where research on viruses like SARS-CoV-2 can be done safely,” says Dr. David Litchfield, Vice Dean of Research and Innovation at Schulich Medicine & Dentistry. “It has become a focal point for dozens of studies involving research through Schulich Medicine & Dentistry, as well as partners from the hospitals and other academic institutions and industries.”
Dr. Litchfield adds that collaboration between hospital partners and scientists has been the key to successful COVID-19 research. “This collaboration has enabled advances leading to new diagnostic testing for COVID-19, as well as studies using MRI or related imaging tools to investigate long-term impacts of the infection on individuals.”
The rapid research response to COVID-19 couldn’t have happened without community and foundation financial support. “Funding support from our hospital Foundation is something we are so grateful for,” says Perkin, referring to St. Joseph’s Health Care Foundation. “They came right out at the beginning and asked how they could help, as did our donors.”
LHSC’s London Health Sciences Foundation and Children’s Health Foundation were also pivotal in research funding during the pandemic. “Funding is a crucial part to how we do hospital research and the Foundations have been important partners in making sure our research continued,” says Young-Ritchie.
As the pandemic continues, so does the research within our community. Hospital research has already improved diagnostics, treatments and patient outcomes related to COVID-19 and helped people all around the world.
“If you look at some of the achievements that have occurred in just a little more than a year, we have had a number of landmark publications on ways to diagnose COVID-19 compared to other respiratory disorders,” notes Dr. Hill. “We have had many rapid advances and it can take a crisis to bring out the best in people. Then things come together quickly, such as expertise, talent and money – and the job gets done.”
Revealing the culprit behind Parkinson’s disease
An estimated 55,000 Canadians are living with Parkinson’s disease. While researchers are advancing therapies to treat symptoms, such as tremors, there is currently no method to stop progression.
To begin addressing this problem, a team of scientists at Lawson Health Research Institute is developing an imaging tracer.
“There’s a protein in the brain called alpha-synuclein (α-syn) that scientists believe is a culprit in causing Parkinson’s disease. The protein forms in ‘clumps’ called Lewy bodies that kill brain cells and potentially lead to disease,” explains Dr. Justin Hicks, Lawson Imaging Scientist. “Unfortunately, we have no way to study it in human brains and this has limited our ability to test therapies against it.”
Efforts have been made to study the elusive protein through modern imaging techniques like positron-emitting tomography (PET). Scientists have attempted to develop a PET probe – a radioactive molecule that targets the specific protein in order to produce highly specific images or scans – but they have been unsuccessful.
Above: Dr. Justin Hicks working in the Nordal Cyclotron & PET Radiochemistry Facility
“Unfortunately, the Lewy bodies caused by α-syn are hard to distinguish from protein clumps found in Alzheimer’s disease and other dementias. This makes it very difficult to know whether a PET probe has found clumps associated with Parkinson’s disease.”
Through a new study, Dr. Hicks and his team are working to find a solution. To do so, they will examine a different but related protein.
“There’s another protein called fatty acid binding protein 3 (FABP3) and one of its roles is to ‘chaperone’ the α-syn protein in human cells. Past studies have shown that levels FABP3 are higher in patients with Parkinson’s disease when compared to healthy controls,” explains Dr. Hicks. “This suggests that high concentrations of FABP3 can be used as an alternate measure of α-syn.”
They hope to measure levels of the FABP3 protein in place of the α-syn protein, and gain a better understanding of the role that both proteins play in the development and progression of Parkinson’s disease. To image Lewy bodies associated with Parkinson’s disease, the researchers are working to produce a PET probe that targets FABP3.
To accomplish this, they will be working in their lab to find a chemical that targets FABP3. Once found, they will attach a radioactive isotope to the chemical and produce a finished tracer. The tracer will then be tested in preclinical models.
Once injected, the PET probe will find and stick to FABP3. The PET isotope will emit a small amount of radioactivity and these emissions will show up as PET images.
“The ultimate goal is to develop a PET probe that can be used to distinguish Parkinson’s disease from other neurodegenerative diseases. The probe could also be used to assess new therapies that reduce levels of the α-syn protein,” says Dr. Hicks. “If successful, we hope this research will lead to a better understanding of the progression of Parkinson’s disease and ways to prevent it.”
Dr. Hicks and his team are being funded for this project through Lawson’s Internal Research Fund (IRF) competition. “Lawson’s IRF is extremely important for early career researchers. It allows us to generate data and publications to then apply for larger external funding. It also permits an added level of risk to pursue projects that may not reach their end goal but often spur new lines of research.”
Above: A graphic depiction of this research project and its goals.
Robarts Research Institute presents 2016 Leaders in Innovation Dinner
Schulich School of Medicine & Dentistry is pleased to announce award-winning actor and director Alan Alda will be the featured guest at the 2016 Leaders in Innovation Dinner.
Alan Alda has enjoyed a 40-year career portraying some of the most memorable characters in television and film.
When not garnering accolades for his roles in front of and behind the camera, he is a visiting professor and a founding member of Stony Brook University’s Alan Alda Center for Communicating Science, where he develops innovative programs on how scientists communicate to the public.
Alan Alda will share a keynote presentation and take part in an engaging armchair discussion about his life, career and passion for communicating science.
Date: Thursday, November 10, 2016
Time: Reception - 5:30 p.m. | Dinner - 6:30 p.m.
Location: London Convention Centre, 300 York Street, London, ON
Ticket price: $250.00
Register by: Tuesday, November 1, 2016
To purchase tickets, please visit the event website.
See the Line: Concussion Research and Awareness - CME & Symposium
Learn the latest in sport related brain injury evaluation and treatment - presented by the Schulich School of Medicine & Dentistry. Once again this year, we will be offering a full-day CME inclusive of the afternoon See the Line Community Symposium that will educate you on the latest in concussion research - hearing from world-class medical experts, health care advocates and professional athletes through the following series of events:
Morning: Continuing Medical Education (CME)
Registration: Registration is required. Registration fees apply for physicians and allied health care professionals.
Confirmed speakers include Dr. Lisa Fischer and Dr. Jason Mihalik. More speakers and a formal agenda will be announced in the coming weeks. Keep checking back for more information.
Who Attends? Physicians, allied health care professionals, medical and nursing students, residents
CME Session Options:
Full-day CME (8:30 a.m. - 5:00 p.m.):
Morning session in Dental Science Building, Rm. 1002, Western University
Afternoon session in Natural Sciences Centre, Rm. 145, Western University
* $100 for physicians and allied health care professionals. Residents and medical students are free.
Morning CME only (8:30 a.m. - 12:00 p.m.):
Dental Science Building, Rm. 1002, Western University
* $100 for physicians and allied health care professionals. Residents and medical students are free.
Afternoon Symposium only (1:00 - 5:00 p.m.):
Natural Sciences Centre, Rm. 145, Western University
* Attend the complimentary Community Information Symposium and earn CME credits by registering for the afternoon Symposium through Continuing Professional Development (CPD).
* You must register through CPD to earn CME credits.
Afternoon: Community Information Symposium
Time: 1:00 - 5:00 p.m.
Location: Natural Sciences Centre, Rm. 145, Western University
Registration: Registration is required. Free for all to attend.
Learn the latest concussion news and research from an exciting lineup of world-class experts and researchers. You will also hear personal stories from a panel of professional athletes about the impact concussions have had on their careers and lives.
Confirmed speakers include Dr. Douglas Fraser, Dr. David Mulder and Ms. Lisa MacLeod, MPP. The 2016 line up of athletes will be announced in the coming weeks. Keep checking back for more information.
Who Attends? Coaches, athletes, teams, parents, educators, students, health care professionals and media
For more information, including event registration please visit the See the Line website.
Study will use 3D bio-artificial tissue model to improve understanding of wound healing after glaucoma surgery
James Armstrong, an MD/PhD student at Western University’s Schulich School of Medicine & Dentistry conducting research at Lawson Health Research Institute, is creating a 3D bio-artificial tissue model to study wound healing following glaucoma surgery.
There are currently no curative treatments for glaucoma, the leading cause of irreversible blindness world-wide. The only therapy that can delay the progression of the disease is the reduction of intra-ocular pressure, which can be accomplished by taking drugs or undergoing surgery. Surgery is usually a last resort if pharmacological treatment is unsuccessful as many of these surgeries fail due to excessive healing of the surgical wound. A dense, scar-like tissue can develop at the surgical site, which blocks the pressure-lowering effect and leads to surgical failure, revision and even blindness.
Armstrong will identify risk factors for fibrotic glaucoma surgery failure through reviews of electronic patient records and literature. Using the constructed model of the ocular tissue involved in glaucoma surgery, he will simulate the surgical wound to study the physiology of how the tissue heals and test potential drugs designed to modulate the wound healing process.
The project has been awarded a Lawson Internal Research Fund (IRF) Studentship, and is supervised by Lawson scientist and St. Joseph’s Health Care London physician Dr. Cindy Hutnik.
“Right now there is a shift happening towards earlier surgical interventions for glaucoma so an understanding of the wound healing response is critical to ensure safe and successful outcomes for patients,” Armstrong says. “Future work in this area could include developing a diagnostic test to inform physicians of a patients’ likelihood of excessive healing before the patient even sets foot in the operating room. This will allow surgeons to ‘customize’ how they pre-treat each individual patient with wound healing modulating drugs.”
Although this study is focused on wound healing within the eye, the same processes are at work in many other diseases. Understanding and having the ability to manipulate wound healing mechanisms could have widespread applicability, not only for glaucoma, but also for other diseases such as atherosclerosis, interstitial pulmonary fibrosis, hepatic fibrosis, systemic sclerosis or muscular dystrophy, as well as heart, kidney or liver failure.
“The IRF has given me the opportunity to pursue research in an area where any progress could impact a significant portion of the population,” Armstrong says. “It’s a great way for researchers who are early in their career to get a foot in the door. It allows them to collect the amount of data necessary to receive funding from larger granting agencies.”
The IRF is designed to provide Lawson scientists and students the opportunity to obtain start-up funds for new projects with the potential to obtain larger funding, be published in a high-impact journal, or provide a clinical benefit to patients. Funding is provided by the clinical departments of London Health Sciences Centre and St. Joseph’s Health Care London, as well as the hospital foundations (London Health Sciences Foundation and St. Joseph's Health Care Foundation).
Tomorrow’s scientists tour Lawson research facilities
A group of senior chemistry students from H.B. Beal Secondary School visited Lawson Health Research Institute (Lawson) facilities at St. Joseph’s Hospital on Wednesday, November 8. In addition to learning about Lawson’s world-renowned imaging research, the group toured the Cyclotron and PET Radiochemistry Facility and Dr. Alexandre Legros’ brain stimulation lab.
The students first learned about Lawson’s simultaneous PET/MRI – the first in Canada – and its associated research. Led by Dr. Jonathan Thiessen, Lawson imaging scientist, the presentation focused on the benefits of combining Positron Emission Tomography (PET) with Magnetic Resonance Imaging (MRI) across multiple disciplines.
Above: Dr. Jonathan Thiessen discusses Lawson's simultaneous PET/MRI
Benjamin Wilk, a PhD candidate working under Dr. Thiessen’s supervision, presented on his research which is focused on developing methods to image the heart after myocardial infarction, or heart attack, using PET/MRI. Qi Qi, another of Dr. Thiessen’s PhD candidates, discussed his research that looks at multimodal imaging to evaluate tumour perfusion and glycolysis in brain tumours.
"It is an incredible opportunity to present our work to high school students,” said Dr. Thiessen. “By seeing examples of the research happening in their own community, my hope is that some of them will be inspired and work hard to become the scientists and healthcare professionals of tomorrow."
The students were then split into two tour groups. The first group toured Lawson’s Nordal Cyclotron and PET Radiochemistry Facility with the facility’s director, Dr. Michael Kovacs; Jeff Corsaut, engineer; and Dr. Justin Hicks, Lawson imaging scientist.
Above: Dr. Justin Hicks provides a tour of The Cyclotron and PET Radiochemistry Facility
The Cyclotron and PET Radiochemistry Facility is used to produce positron-emitting radiopharmaceuticals (PERs). PERs are injected into patients undergoing a positron emission tomography (PET) scan. The half-life of the radioactive isotopes in PERs is short, which necessitates generating them with a cyclotron that is in close proximity to the clinic where they are used.
The students learned how PERs are produced in the Cyclotron and research being conducted with PERs to advance imaging of complex diseases.
The second group toured Dr. Alexandre Legros’ brain stimulation lab which is part of the Bioelectromagnetics and Human Threshold Research Group at Lawson. Dr. Legros’ research focuses on the effects of specific electromagnetic stimuli - from deep brain stimulation to power-frequency magnetic fields - on human brain processing, motor control and cognitive functions. The students were guided by lab manager, Michael Corbacio, and postdoctoral scholar, Dr. Sebastien Villard.
Above: Dr. Sebastien Villard (second from right) and Michael Corbacio (far right) provide a demonstration of research being conducted in Dr. Alexandre Legros' Bioelectromagnetics and Human Threshold Research Group
The two groups of students then traded places, touring the facility they had not yet visited.
“The H.B Beal senior chemistry class was impressed and grateful with the opportunity to visit the facilities at Lawson Health Research Institute,” said Andrew Holmes, the class’ teacher and head of science at H.B. Beal. “The presentations, cyclotron tour and research lab gave students some valuable insight into some of the roads available to them with a scientific path in education. Students were particularly impressed with how enthusiastic and excited the researchers were in talking about their work at Lawson, and came away with a very positive view of scientific career paths.”
Two Lawson researchers each receive $400K CIHR grants to improve kidney care
Two researchers at Lawson Health Research Institute have each been awarded $400,000 as part of the Canadian Institute of Health Research’s (CIHR) new Health System Impact Embedded Early Career Researcher Awards.
The funding will see the researchers apply their skills to find and implement solutions to improve kidney care by focusing on challenges in the health-care system.
Dr. Kyla Naylor and Dr. Danielle Nash will each spend four years working with provincial organizations. Dr. Naylor will work with the Trillium Gift of Life Network -Ontario Health, which is the organization responsible for coordinating provincial organ and tissue donation and transplant services. Dr. Nash will work with the Ontario Renal Network - Ontario Health, which is the organization responsible for managing delivery of advanced kidney services in the province.
“The treatment options for kidney failure is either a kidney transplant or dialysis. The majority of Canadians who have kidney failure receive dialysis,” says Dr. Naylor, who is an Associate Scientist at Lawson and an Adjunct Scientist at ICES. “However, a kidney transplant compared to dialysis can improve a patients’ quality of life, can give on average 10 more years of survival, and when compared to dialysis, can save the health-care system millions of dollars.”
In her research program, Dr. Naylor will begin by developing a kidney transplant measurement framework that will enable continuous performance monitoring and increase equitable access to transplant.
“The first goal of this project will allow kidney transplant centres and regional renal programs to evaluate their performance and set goals towards improvement,” Dr. Naylor says. “The second is to improve kidney transplant education materials to provide patients with the information to make an informed decision about kidney transplant, and the third is to address geographical barriers to transplantation.”
Dr. Naylor will be using ICES data, which includes administrative health-care data for Ontario’s 14.5 million residents, with the goal of eventually making access to kidney transplantation more equitable for the thousands of Canadians living with kidney failure.
The goal of Dr. Nash’s research program is to use a learning health system model to better understand patient-identified gaps in kidney care across Ontario, and to develop solutions to fill these gaps in collaboration with the Ontario Renal Network and patient partners.
“Chronic kidney disease is a serious illness that can lead to kidney failure. The best way to prevent kidney failure is to detect chronic kidney disease early and provide optimal care during this time,” explains Dr. Nash, who is also an Epidemiologist and Scientist with London Health Science Centre’s (LHSC) Kidney Dialysis and Transplantation Program. “Since many patients do not have symptoms, it can go unnoticed for a long time. However, it can be detected using simple blood and urine tests.”
Province-wide data from ICES Ontario and the Ontario Renal Network will be used for the research data.
As part of both studies, the researchers will also be interviewing health-care providers and patients to assess additional barriers to treatment.
“One in four patients do not see a nephrologist in a timely manner and 60 per cent are not receiving adequate time in multidisciplinary kidney care clinics before initiating dialysis,” says Dr. Nash. “Education on treatment options (typically dialysis or a kidney transplant) needs to happen early for patients who are at high risk for kidney failure, so they can make an informed decision about treatment.”
Communications Consultant & External Relations
Lawson Health Research Institute
T: 519-685-8500 ext. ext. 64059
C: 226-919-4748
@email
Understanding the vaginal microbiome essential to human health
There are trillions of microorganisms inhabiting your body. The majority of these are positive and essential to your health. They include those microorganisms found in the female reproductive system – a highly diverse environment that is crucial to human survival.
Understanding the microorganisms that inhabit the vagina, also known as the vaginal microbiome, is extremely important for women, their offspring and sexual partners. Dr. Gregor Reid recognizes this importance through his research into lactobacilli, the dominant organisms present in the healthy vagina of most women.
Dr. Reid is a Lawson microbiome and probiotics scientist and director of the Canadian Research and Development Centre for Probiotics. His interest in the vaginal microbiome began over 33 years ago.
“In the human gut, the microbiome differs with diet. But there is a global similarity to the vaginal microbiome,” said Dr. Reid. “From early in my career, I suspected a connection between this uniformity and the female’s critical role in reproduction.”
Harmful bacteria, also known as pathogens, can invade the vaginal microbiome to produce a more highly diverse state. This leads to the displacement of lactobacilli. It can also lead to bacterial vaginosis (BV) and the easier contraction of urinary tract infections (UTIs). These two ailments account for numerous physician visits each year and a reduction in a woman’s quality of life.
Mediating pregnancy and infant development
Research suggests that lactobacilli mediate complex changes that occur during pregnancy. If harmful pathogens invade and persist, inflammation and premature delivery can occur during pregnancy.
“The mechanisms behind the displacement of lactobacilli are not clear,” says Dr. Reid. “However, a number of factors can increase risk of BV. These include douching, sexual intercourse, lower estrogen levels and aging. It’s crucial that we conduct further research into these processes.”
Studies also suggest that the human fetus is exposed to the mother’s lactobacilli prior to birth, in addition to exposure during vaginal birthing. Again, understanding of this process and its significance is limited but warrants further investigation, says Reid. We need to further understand how exposure affects an infant’s immunity, metabolism and behavior in both early and later life.
“We’re seeing a dramatic rise in C-sections and a drop in breastfeeding,” says Reid. “If a developing child is not fully exposed to the mother’s lactobacilli, does this provide an opportunity for harmful bacteria to proliferate? This may cause repercussions to the offspring’s own future reproductive health.”
The role of probiotics
As research begins to focus on restoring a lactobacilli-dominant state, probiotics have been explored. However, attempts have presented challenges. “When probiotics are administered vaginally in a dried form, the lactobacilli fail to colonize long-term,” says Dr. Reid. “A study introducing lactobacilli in more natural form may lead to successful colonization. This has been the case in other areas like fecal transplantation.”
Challenges and opportunities
There are a number of other challenges when it comes to the study of the vaginal microbiome. This includes the lack of suitable animal models. While there have been recent developments that may lead to better recreations of a female microbiome, Dr. Reid explains that it will be difficult to mimic the many complexities of the female reproduction system. These include the menstrual cycle, immune responses, the use of douches, sexual intercourse and more.
“To fully understand female health, reproduction and infant development, we need to better understand lactobacilli,” said Dr. Reid. “We know that lactobacilli may help to combat herpes and environmental toxins, improve sperm motility, and even self-cure episodes of UTI and/or BV. What we are slowly uncovering is an understanding of the processes behind these interactions.”
Dr. Reid recently published a paper on this subject, "Cervicovaginal Microbiomes–Threats and Possibilities", in the publication Trends in Endocrinology & Metabolism. Dr. Reid’s own research is currently focused on compounds with the capacity to expand the proportion of lactobacilli at the expense of pathogens. The goal of this research is to improve the health of women across Canada and around the world.
Work with Us: Scientist Opportunities
Current Scientist Opportunities
Find other career opportunities with Lawson Research Institute posted in St. Joseph's Careers portal.
You are invited to London Health Research Day
LHRD 2021 is going virtual, offering a wide range of workshops, a keynote lecture, and several days dedicated to research presentations.
- Research posters will be available to view from May 7 to May 18.
- Workshops and the keynote presentation will take place on May 11 from 10:00 a.m. – 3:30 p.m.
Register today for an opportunity to review research presentations or to take part in the workshops or keynote lecture. Due to a limited attendance capacity, pre-registration is required. Don’t miss your opportunity to take part in LHRD 2021!
Please note: If you are a poster presenter, you will receive an email from Janelle Pritchard with instruction on your pre-registration. Please follow directions as outlined in her communication for registration and to sign up for the sessions taking place on May 11.
Registration deadline is May 5, 2021.
EVENT DAY AGENDA
View the full event schedule.
Morning Workshops
10:15 – 11:45 a.m. – Workshop options:
Science to Business Network Presents (S2BN): Insights into Industry- Exploring Careers for Graduate Students
Hosted by S2BN London, this workshop features a panel of esteemed industry professionals who will discuss their unique career journeys, the skills and knowledge needed to excel in their positions, and steps graduate students can take to enter these industries and succeed. This 90-min session will consist of a panel discussion moderated by Dr. Bruce Seet, Director of Medical Affairs at Sanofi Pasteur and President of S2BN. The panel discussion will be followed by an opportunity to network and interact with the panelists.
Reforming Equity, Diversity and Inclusion in Academic and Professional Health Settings: Fundamentals, Gaps and Accountability
In this 90-minute interactive workshop, learn directly from advisors, experts, and trainees on how to adopt equity, diversity, and inclusion practices in academic and health research health settings.
The Lucille & Norton Wolf Health Research Lecture Series – featuring Andrew Au
12:00 – 1:30 p.m.
Andrew Au is a modern business leader who helps global blue-chip brands respond to the new culture and nature of work. During his keynote lecture, Andrew will share how digital transformation is providing new opportunities for innovation across the health care and health research sectors and how is it revolutionizing the ways we interact with each other, our teams, patients, and the broader community.
Afternoon Workshops
1:30 – 3:30 p.m. - Workshop options:
Knowledge Mobilization via The Conversation Canada
The Conversation Canada is a daily independent online publication, delivering analysis and explanatory journalism from the academic and research community directly to the public. Deputy Editor Hannah Hoag and Editor-in-Chief Scott White will explain the mission of The Conversation Canada, offer some background on how it helps academics with knowledge mobilization and give some tips on how to pitch a really great story idea. This is an interactive workshop where participants are encouraged to bring story ideas to discuss.
Interview Skills/Strategies for Academic and Non-academic Positions
This workshop consists of two concurrent sessions focused on interview skills/strategies needed for academic and non-academic job positions. During the workshop, a panel of speakers who have vast proficiency in the recruitment process will share their experiences with attendees.
You’re invited to London Health Research Day and Exchange
Register today for London Health Research Day (LHRD) and experience the largest research-focused activity in Southwestern Ontario.
With hundreds of presentations from top learners, LHRD is your opportunity to learn about health research being conducted in the city of London. Dr. Janet Smylie, an international leader in the field of Indigenous health and health research, is this year’s keynote speaker as part of The Lucille & Norton Wolf Health Research Lecture Series.
Dr. Smylie will also join a group of local and national researchers as part of a new event - Exchange: A London Health Research Day Forum on Diversity and Inclusivity.
Exchange: A London Health Research Day Forum on Diversity and Inclusivity
Exchange aims to foster conversations around equity, diversity and inclusivity in the careers of health researchers, including gender, and how we can work together to identify and implement solutions.
- Date: Wednesday, May 9, 2018
- Time: 6:00 - 9:00 p.m.
- Location: North Campus Building, Western University. See campus map.
- Registration is required.
The evening’s presenters include:
- Dr. Janet Smylie – An international leader in the field of Indigenous health and health research
- Dr. Greta Bauer – A scientist at Western University’s Schulich School of Medicine & Dentistry with a special interest in LGBTQ health
- Dr. Alysha Croker – Current manager of the Canada Excellence Research Chairs (CERC) and the Canada First Research Excellence Fund (CFREF) programs at the Tri-agency Institutional Program Secretariat, and previous lead on the development of the Canadian Institutes of Health Research’s (CIHR’s) Equity Strategy
- Shantal Feltham – Founder of Stiris Research, a London-based North American clinical trial management company
- Learners from Schulich Medicine & Dentistry, training in labs at Western and Lawson Health Research Institute
London Health Research Day 2018
- Date: Thursday, May 10, 2018
- Time: Registration begins at 7:30 a.m. View the full event schedule.
- Location: London Convention Centre. See location map and transportation/parking details.
- Guest registration is required for the lunchtime keynote speaker and the networking and awards reception.
London Health Research Day is presented in partnership by Lawson Health Research Institute and the Schulich School of Medicine & Dentistry.
Youth report improved wellbeing as result of tailored mental health services
LONDON, ON - In a new study from Lawson Health Research Institute and Western University, researchers partnered with youth receiving care at the First Episode Mood and Anxiety Program (FEMAP) at London Health Sciences Centre (LHSC) to better understand personal perspectives on care and treatment outcomes. The study found that patients experienced lasting improvements in managing their symptoms and improvements in academics, work performance and relationships, and they reported that these benefits involved being empowered by feelings of self-acceptance.
The study included 22 patients from FEMAP, a novel outpatient mental health program at LHSC that provides treatment to ‘emerging adults,’ ages 16 to 25, with emotional concerns that fall into the categories of mood and anxiety symptoms. Treatment at FEMAP takes a patient-centred approach and the research involved looking at what is meaningful and valuable to patients during their care journey.
“The transition from adolescence to adulthood is challenging. FEMAP employs an innovative model of care tailored to the needs of this complex population,” said Dr. Elizabeth Osuch, a clinician-scientist at Lawson, associate professor at Western University’s Schulich School of Medicine & Dentistry and medical director at FEMAP. “By engaging patients in a reflection of their experience, we can learn how effective the program is from the patient perspective.”
Participants shared their experiences through open-ended interviews with Dr. Osuch’s research team. Interview transcripts were collected and analyzed to determine common themes around treatment and outcomes. These themes were then presented back to the research participants for validation.
The study found that treatment led to development of coping strategies to better manage symptoms. Research participants credited these strategies for better functioning in academics, careers and personal relationships. Challenges in these areas are common among emerging adults and are often stressors that lead to youth seeking mental health care.
Participants characterized their treatment at FEMAP as an important investment in their mental health and wellbeing, and credited a collaborative partnership with their care provider for keeping them engaged in treatment. They appreciated the ease of accessing treatment at FEMAP where they could receive care from a psychiatrist, social worker, addictions counsellor, family counsellor and a psychologist, depending on their needs.
The research found that the complexities of treatment were initially frustrating to patients as they were seeking an “easy fix” to their mental health concerns, but they ultimately appreciated that mental health recovery is a journey. They valued that care providers partnered with them to set long-term treatment goals, choose the best treatment options and provide support both during and between appointments.
“Patients may prefer FEMAP over other mental health services because the care is tailored to emerging adults,” said Justin Arcaro, first author on the study and a former MSc candidate at Schulich Medicine & Dentistry and research associate at FEMAP. “There’s an important balance between recognizing emerging adults’ personal autonomy and their need for comprehensive support.”
Study results demonstrated that through treatment at FEMAP, patients realized they are not alone in their mental health journey which led to improved self-acceptance and self-compassion. Participants reported feeling empowered to create meaningful changes in their lives.
Participants also discussed the decision to seek mental health care in the first place. Many struggled with the decision of whether or not treatment was needed. “This shows a need for targeted campaigns to help emerging adults distinguish between normative feelings and those that indicate a need for help,” said Dr. Osuch.
This study also aligns with other research projects at FEMAP that suggest a need for targeted education campaigns about mental health care as a process with solutions that are not necessarily quick or easy. The research team highlights the importance of these findings in informing future funding decisions and policy around mental health care for emerging adults. The findings emphasize the need for quick engagement with a trusted care provider and an integrated treatment team that can partner with patients to support them while enhancing independent growth and self-acceptance.
The study, “Emerging adults’ evaluation of their treatment in an outpatient mood and anxiety disorders program,” is published in Emerging Adulthood.
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Lawson Health Research Institute is one of Canada’s top hospital-based research institutes, tackling the most pressing challenges in health care. As the research institute of London Health Sciences Centre and St. Joseph’s Health Care London, our innovation happens where care is delivered. Lawson research teams are at the leading-edge of science with the goal of improving health and the delivery of care for patients. Working in partnership with Western University, our researchers are encouraged to pursue their curiosity, collaborate often and share their discoveries widely. Research conducted through Lawson makes a difference in the lives of patients, families and communities around the world. To learn more, visit www.lawsonresearch.ca.
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Youth report improved wellbeing as result of tailored mental health services, study finds
In a new study from Lawson Health Research Institute and Western University, researchers partnered with youth receiving care at the First Episode Mood and Anxiety Program (FEMAP) at London Health Sciences Centre (LHSC) to better understand personal perspectives on care and treatment outcomes. The study found that patients experienced lasting improvements in managing their symptoms and improvements in academics, work performance and relationships, and they reported that these benefits involved being empowered by feelings of self-acceptance.
The study included 22 patients from FEMAP, a novel outpatient mental health program at LHSC that provides treatment to ‘emerging adults,’ ages 16 to 25, with emotional concerns that fall into the categories of mood and anxiety symptoms. Treatment at FEMAP takes a patient-centred approach and the research involved looking at what is meaningful and valuable to patients during their care journey.
“The transition from adolescence to adulthood is challenging. FEMAP employs an innovative model of care tailored to the needs of this complex population,” said Dr. Elizabeth Osuch, a clinician-scientist at Lawson, associate professor at Western University’s Schulich School of Medicine & Dentistry and medical director at FEMAP. “By engaging patients in a reflection of their experience, we can learn how effective the program is from the patient perspective.”
Participants shared their experiences through open-ended interviews with Dr. Osuch’s research team. Interview transcripts were collected and analyzed to determine common themes around treatment and outcomes. These themes were then presented back to the research participants for validation.
The study found that treatment led to development of coping strategies to better manage symptoms. Research participants credited these strategies for better functioning in academics, careers and personal relationships. Challenges in these areas are common among emerging adults and are often stressors that lead to youth seeking mental health care.
Participants characterized their treatment at FEMAP as an important investment in their mental health and wellbeing, and credited a collaborative partnership with their care provider for keeping them engaged in treatment. They appreciated the ease of accessing treatment at FEMAP where they could receive care from a psychiatrist, social worker, addictions counsellor, family counsellor and a psychologist, depending on their needs.
The research found that the complexities of treatment were initially frustrating to patients as they were seeking an “easy fix” to their mental health concerns, but they ultimately appreciated that mental health recovery is a journey. They valued that care providers partnered with them to set long-term treatment goals, choose the best treatment options and provide support both during and between appointments.
“Patients may prefer FEMAP over other mental health services because the care is tailored to emerging adults,” said Justin Arcaro, first author on the study and a former MSc candidate at Schulich Medicine & Dentistry and research associate at FEMAP. “There’s an important balance between recognizing emerging adults’ personal autonomy and their need for comprehensive support.”
Study results demonstrated that through treatment at FEMAP, patients realized they are not alone in their mental health journey which led to improved self-acceptance and self-compassion. Participants reported feeling empowered to create meaningful changes in their lives.
Participants also discussed the decision to seek mental health care in the first place. Many struggled with the decision of whether or not treatment was needed. “This shows a need for targeted campaigns to help emerging adults distinguish between normative feelings and those that indicate a need for help,” said Dr. Osuch.
This study also aligns with other research projects at FEMAP that suggest a need for targeted education campaigns about mental health care as a process with solutions that are not necessarily quick or easy. The research team highlights the importance of these findings in informing future funding decisions and policy around mental health care for emerging adults. The findings emphasize the need for quick engagement with a trusted care provider and an integrated treatment team that can partner with patients to support them while enhancing independent growth and self-acceptance.
The study, “Emerging adults’ evaluation of their treatment in an outpatient mood and anxiety disorders program,” is published in Emerging Adulthood.
Above: Dr. Elizabeth Osuch and Justin Arcaro